Lightsheet microscopy system
LAC lab, CBC lab
我們開發並利用多光子或是層光顯微鏡, 轉盤式共軛焦顯微鏡，我們可以高速的取得四維的活體影像，進而分析神經系統訊號傳遞、藥物釋放、癌症細胞動態活動等等活體反應。如果你想了解更多層光顯微鏡，可以參考以下科普文章：https://www.tiri.narl.org.tw/Files/Doc/Publication/InstTdy/225/02250000-4.pdf
We collaborate with Prof. Bi-Chang Chen's lab to build a fully automated Bessel ligthsheet microscopy, which can perform 40HZ imaging rate and 3D volumetric image.
The axiel swipe lightsheet is suitable for imaging various sample with different size and with different image resolution requirements.
This video was acquired with Bessel lightsheet microscopy. Imaging depth was 100 um, color coded. These olfactory projection neurons were labeled in GH146-Gal4>UAS-GCaMP6m flies. This fly was experiencing Apple Cider Vinegar stimuli.
We manually selected buttons of GH146 neurons and calculate each of their responses toward ACV stimuli
