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Publication

  1. Ya-Han Chuang#, Yueh-Feng Wu#, Ya-Hui Lin, Yu-Xian Zhou, Shao-Chun Hsu, Ann-Shyn Chiang, Sung-Jan Lin* and Li-An Chu*, Expansion microscopy for super-resolution imaging of collagen-abundant tissues.  Small Structures, Accepted, 2024

  2. Yalamandala, B. N., Chen, Y. J., Lin, Y. H., Huynh, T. M. H., Chiang, W. H., Chou, T. C., Liu, H. W., Huang, C. C., Lu, Y. J., Chiang, C. S., Chu, L. A., & Hu, S. H. (2024). A Self-Cascade Penetrating Brain Tumor Immunotherapy Mediated by Near-Infrared II Cell Membrane-Disrupting Nanoflakes via Detained Dendritic Cells. ACS nano, 18(28), 18712–18728

  3. Li-An Chu, Chu-Yi Tai, Ann-Shyn Chiang, Thirst-driven hygrosensory suppression promotes water seeking in Drosophila. PNAS, Accepted, 2024.

  4. Po-Kai Luo, Hui-Min Ho, Min-Chun Chiang, Li-An Chu, Ya-Han Chuang,
    Ping-Chiang Lyu, I-Chen Hu, Wan-An Chang, Sheng-Yao Peng, Jayachandran Jayakumar,
    Hsin-Lung Chen, Ming-Hsi Huang,* and Hsing-Wen Sung, pH-Responsive 𝜷-Glucans-Complexed mRNA in LNPs as an Oral Vaccine for Enhancing Cancer Immunotherapy, Advanced Materials, 244, 2404830, June 2024

  5. Mohammed Bin Abubaker, Fu-Yu Hsu, Kuan-Lin Feng, Li-An Chu, J. Steven de Belle, Ann-Shyn Chiang, Asymmetric neurons are necessary for olfactory learning in the Drosophila brain, Current Biology, Feb, 5, 2024

  6. GaryHan Chang, Meng-Yun Wu, Ling-Hui Yen, Da-Yu Huang, Ya-Hui Lin, Yi-Ru Luo, Ya Ding Liu, Bin Xu, Kam W. Leong, Wen-Sung Lai, Ann-Shyn Chiang, Kuo-Chuan Wang, Chin-Hsien Lin, Shih-Luen Wang, Li-An Chu*,Isotropic multi-scale neuronal reconstruction from high-ratio expansion microscopy with contrastive unsupervised deep generative models, Computer Methods and Programs in Biomedicine, 244, Feb. 2024 (IF:7.027)

  7. Ya-Hui Lin , Li-Wen Wang , Yen-Hui Chen , Yi-Chieh Chan , Shang-Hsiu Hu , Sheng-Yan Wu , Chi-Shiun Chiang , Guan-Jie Huang , Shang-Da Yang , Prof. Shi-Wei Chu , Kuo-Chuan Wang , Dr. Chin-Hsien Lin , Pei-Hsin Huang , Hwai-Jong Cheng , Bi-Chang Chen*, Li-An Chu*, Revealing intact neuronal circuitry in centimeter-sized formalin-fixed paraffin-embedded brain, eLife (accepted) doi: https://doi.org/10.1101/2022.11.28.518189

  8. Min-Ren Chiang*, Ya-Hui Lin*, Wei-Jie Zhao, Hsiu-Ching Liu, Ru-Siou Hsu, Tsu-Chin Chou, Tsai-Te Lu, I-Chi Lee, Lun-De Liao, Shih-Hwa Chiou, Li-An Chu*, Shang-Hsiu Hu*, In Situ Forming of Nitric Oxide and Electric Stimulus for Nerve Therapy by Wireless Chargeable Gold Yarn-Dynamos, Advanced Science, 22, Oct, 2023

  9. Hsuan-Yu Mu, Chiao-Min Lin, Li-An Chu, Ya-Hui Lin, Ji Li, Chao-Yu Liu, Hsi-Chien Huang, Sheng-Liang Cheng, Tsung-Ying Lee, Hsin Mei Lee, Hsin-Min Chen, Yun-Jen Tsai, Yunching Chen, Jen-Huang Huang, Ex Vivo Evaluation of Combination Immunotherapy Using Tumor-Microenvironment-on-Chip, Advanced Healthcare Materials, 25 Sep 2023

  10. Yi-Chieh Chan*, Ya-Hui Lin *, Hsiu-Ching Liu a, Ru-Siou Hsu c, Min-Ren Chiang a, Li-Wen Wang a b, Tsu-Chin Chou d, Tsai-Te Lu e f g, I-Chi Lee a, Li-An Chu*, Shang-Hsiu Hu*, In situ magnetoelectric generation of nitric oxide and electric stimulus for nerve therapy by wireless chargeable molybdenum carbide octahedrons, Nanotoday, Volume 51, Aug, 2023 

  11. Kuan-Hung Chen, Nhien Nguyen, Tun- YuHuang, Yu-Jung Lin, Yu-Tzu Yu, Hsiang-Lin Song, Jui-To Wang, Khanh Nguyen, Hsin-Lung Chen, Li-An Chu, Hui-HuaKenny Chiang, Hsing-Wen Sung, Macrophage-Hitchhiked Orally Administered Β-Glucans-Functionalized Nanoparticles as “Precision-Guided Stealth Missiles” for Targeted Pancreatic Cancer Therapy, Advanced Materials, June 26, 2023

  12. Pooyan Heravi · Li‐An Chu* · Da‐Jeng Yao*, Reorientation of the interface between two miscible solutions of equal density, Experimental Thermal and Fluid Science, 2023, 144, 110854

  13. Pooyan Heravi · Li‐An Chu* · Da‐Jeng Yao*, An empirical model for lateral flow in horizontally stratified flows, Microfluidics and Nanofluidics, 2023, 27:4

  14. Guan-Jie Huang, Pei-Chen Lai, Ming-Wei Shen, Jia-Xuan Su, Jhan-Yu Guo, Kuo-Chuan Chao, Peng Lin, Ji-Xin Cheng, Li-An Chu, Ann-Shyn Chiang, Bo-Han Chen, Chih-Hsuan Lu, Shi-Wei Chu, and Shang-Da Yang, Towards stimulated Raman scattering spectro-microscopy across the entire Raman active region using a multiple-plate continuum, Optics Express, 2022, Vol 30, Issue 21, pp. 38975-38984.

  15. Ru-Siou Hsu, Ssu-Ju Li, Jen-Hung Fang, I-Chi Lee, Li-An Chu, Yu-Chun Lo, Yu-Jen Lu, You-Yin Chen & Shang-Hsiu Hu, Wireless charging-mediated angiogenesis and nerve repair by adaptable microporous hydrogels from conductive building blocks. Nature Communications, 2022, 13, 5172. 

  16. Wei Cheng, Yu-Lin Su, Hao-Hsiang Hsu, Ya-Hui Lin, Li-An Chu, Wei-Chen Huang, Yu-Jen Lu, Chi-Shiun Chiang, and Shang-Hsiu Hu. Rabies Virus Glycoprotein-Mediated Transportation and T Cell Infiltration to Brain Tumor by Magnetoelectric Gold Yarnballs. ACS Nano, 2022, 16, 3, 4014–4027

  17. (與台大醫學院合作) Chin-Hsien Lin, MD, PhD,* Han-Yi Lin, MS, En-Pong Ho, MS,Yi-Ci Ke, MS, Mei-Fang Cheng, MD, Chyng-Yann Shiue, PhD, Chi-Han Wu, MS, Peng-Hsiang Liao, Angela Yu-Huey Hsu,3 Li-An Chu, PhD,4,5 Ya-Ding Liu,4,5 Ya-Hui Lin,4,5 Yi-Cheng Tai, MD, Chia-Tung Shun, MD, PhD,7 Han-Mo Chiu, MD, PhD,8,9 and Ming-Shiang Wu, MD, PhD9, "Mild Chronic Colitis Triggers Parkinsonism in LRRK2 Mutant Mice Through Activating TNF-α Pathway", Movement Disorders, 2021. 

  18. (與台大生理所合作) Wu, Chen-Yi and Jhang, Jhih-Gang and Lin, Wan-Syuan and Lin, Chih-Wei and Chu, Li-An and Chiang, Ann-Shyn and Ho, Han-Chen and Chan, Chih-Chiang and Huang, Shu-Yi, "Dihydroceramide Desaturase Promotes the Formation of Intraluminal Vesicles and Inhibits Autophagy to Increase Exosome Production", iScience, 2021. 41

  19. (與中研院應科中心合作) Li-An Chu*, Shu-Wei Chang, Wei-Chun Tang, Yu-Ting Tseng, Peilin Chen, Bi-Chang Chen*. "5D superresolution imaging for a live cell nucleus”. Curr Opin Genet Dev., 2021;67:77-83.

  20. (與清大工科系合作) Venkanagouda S. Goudar, Manohar Prasad Koduri, Yen-Nhi Ngoc Ta, Yunching Chen, Li-An Chu, Long-Sheng Lu,* and Fan-Gang Tseng* , The Impact of Desmoplastic Tumor Microenvironment for Colon Cancer Drug Sensitivity: A Study with 3D Chimeric Tumor Spheroids, ACS Applied Materials & Interfaces. 2021. Online ahead of print.

  21. (與清大生科系合作) Ya-Chu Chang, Yu-Xiang Peng, Bo-Hua Yu, Henry C. Chang, Pei-Shin Liang, Ting-Yi Huang, Chao-Jie Shih, Li-An Chu & Tzu-Kang Sang, VCP maintains nuclear size by regulating the DNA damage-associated MDC1–p53–autophagy axis in Drosophila, Nature Communications, 2021. 12:4258.

  22. (與香港中文大學合作) Zhiqiang Fu, Qiang Geng, Jialong Chen, Li-An Chu, Ann-Shyn Chiang, Shih-Chi Chen. Light field microscopy based on structured light illumination. Optics Letters, 2021. 12; 7:3887-3901

  23. (與台大物理系合作) Huang SH, Irawati N, Chien YF, Lin JY, Tsai YH, Wang PY, Chu LA, Li ML, Chiang AS, Tsia KK and Chu SW*. Optical volumetric brain imaging: speed, depth, and resolution enhancement. J Phys D Appl Phys, 2021. 54:323002.

  24. Li-An Chu*, "Olfactory neurons in Drosophila", Journal of Neuroscience Research, 2020. 98;10:1829-1830.

  25. Li-An Chu*, Chieh-Han Lu*, Shun-Min Yang, Yen-Ting Liu, Kuan-Lin Feng, Yun-Chi Tsai, Wei-Kun Chang, Peilin Chen, Ting-Kuo Lee, Yeu-Kuang Hwu, Ann-Shyn Chiang*, Bi-Chang Chen*, “Rapid single-wavelength lightsheet localization microscopy for clarified tissue”, Nature Communications, 2019. 10:4762

  26. Yun-Chieh Sung, Peiru Jin, Li-An Chu, Fu-Fei Hsu, Mei-Ren Wang, Chih-Chun Chang, Dong-Yu Gao1, Show-Jen Chiou, Jiantai Timothy Qiu, Chu-Chi Lin, Yu-Sing Chen, Yi-Chiung Hsu, Jane Wang, Fu-Nien Wang, Pei-Lun Yu, Ann-Shyn Chiang, Tsai-Te Lu*, Yunching Chen* “Delivery of nitric oxide with a nanocarrier promotes tumour vessel normalization and potentiates anti-cancer therapies”, Nature nanotechnology, 2019. 14;12:1160-1169

  27. Han-Yuan Lin*, Li-An Chu*, Hsuan Yang, Kuo-Jen Hsu, Yen-Yin Lin, Keng-Hui Lin*, Shi-Wei Chu*, and Ann-Shyn Chiang*, “Imaging through the whole brain of Drosophila at λ/20 super-resolution”, iScience, 2019, 164-170.

  28.  Ye Zhang*, Tin Ki Tsang*, Eric Bushong, Li-An Chu, Ann-Shyn Chiang, Mark Ellisman, Jürgen Reingruber, Chih-Ying Su*, “Asymmetric ephaptic inhibition between compartmentalized olfactory receptor neurons”, Nature Communications, 2019, 10:1560.

  29. Lin YY, Wu MC, Hsiao PY, Chu LA, Yang MM, Fu CC, Chiang AS, “Three-wavelength light control of freely moving Drosophila Melanogaster for less perturbation and efficient social-behavioral studies”. Biomed Opt Express, 2015 Jan 13;6(2):514-23. (Impact factor: 3.497)

  30. Ming-Chin Wu*, Li-An Chu*, Po-Yen Hsiao*, Yen-Yin Lin, Tsai-Feng Fu, Chen-Chieh Chi, An-Kuo Hong, Tsung-Ho Liu, Chien-Chung Fu, & Ann-Shyn Chiang, “Optogenetic control of selective neural activity in multiple freely moving Drosophila adults”, PNAS, 2014 Apr 8;111(14):5367-72 (Impact factor: 10) (*: Co-first authors) 

  31. Hui-Hao Lin, Li-An Chu, Tsai-Feng Fu, Barry J. Dickson, Ann-Shyn Chiang*, “Parallel Neural Pathways Mediate CO2 Avoidance Responses in Drosophila”, Science, 2013 Jun 14;340(6138):1338-41. (Impact factor: 37)

  32. C-T Hong, L-A Chu, W-C Lai, A-S Chiang and W-L Fang*, Implementation of a New Capacitive Touch Sensor Using the Nanoporous Anodic Aluminum Oxide (np-AAO) Structure. IEEE Sensor Journal, 2011, Jun 23;11(12);3409-16 (Impact factor: 1.852)

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